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Synonyms of Machado-Joseph Disease
- Autosomal Dominant Spinocerebellar Degeneration
- Azorean Neurologic Disease
- Joseph Disease
- Machado Disease
- Nigrospinodentatal Degeneration
- Spinocerebellar Ataxia Type III (SCA 3)
- Striatonigral Degeneration, Autosomal Dominant Type
- Machado-Joseph Disease Type III (MJD-III)
- Machado-Joseph Disease Type II (MJD-II)
- Machado-Joseph Disease Type I (MJD-I)
Machado-Joseph Disease (MJD-III), also called spinocerebellar ataxia type III, is a rare, inherited, ataxia (lack of muscular control) affecting the central nervous system and characterized by the slow degeneration of particular areas of the brain called the hindbrain. Patients with MJD may eventually become crippled and/or paralyzed but their intellect remains intact. The onset of symptoms of MJD varies from early teens to late adulthood.
Three forms of Machado-Joseph Disease are recognized: Types MJD-I, MJD-II, and MJD-III. The differences in the types of MJD relate to the age of onset and severity. Earlier onset usually produces more severe symptoms.
Machado-Joseph Disease Resources
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