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Sinonasal Undifferentiated Carcinoma

Abstract

You are reading a NORD Rare Disease Report Abstract. NORD’s full collection of reports on over 1200 rare diseases is available to subscribers (click here for details). We are now also offering two full rare disease reports per day to visitors on our Web site.

NORD is very grateful to Andrew Martin, medical student, and Raja Mudad, MD, Associate Professor and Associate Section Chief of Medicine: Hematology-Oncology, Tulane Cancer Center; Director of Hematology-Oncology, Veterans Administration Medical Center, New Orleans, for assistance in the preparation of this report.

Synonyms of Sinonasal Undifferentiated Carcinoma

  • No synonyms found.

Disorder Subdivisions

  • No subdivisions found.

General Discussion

Sinonasal undifferentiated carcinoma (SNUC) is a rare cancer of the nasal cavity and/or paranasal sinuses. Initial symptoms range from bloody nose, runny nose, double vision, and bulging eye to chronic infections and nasal obstruction. It has been associated with several types of papilloma in the nasal cavity, which are benign, but can give rise to malignancy. Prior irradiation for other cancers has been associated with the development of SNUC in a number of cases, and has been associated with a genetic mutation known to be associated with cancer development. Most patients have not had prior irradiation, and no other causes have demonstrated to be significant, though some studies have found that woodworkers and nickel factory workers are generally more susceptible to sinonasal malignancy of all types.

Organizations related to Sinonasal Undifferentiated Carcinoma

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