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Eosinophilic Esophagitis

Abstract

You are reading a NORD Rare Disease Report Abstract. NORD’s full collection of reports on over 1200 rare diseases is available to subscribers (click here for details). We are now also offering two full rare disease reports per day to visitors on our Web site.

NORD is very grateful to Marc E. Rothenberg, MD, PhD, Director and Endowed Chair, Division of Allergy and Immunology, and Professor of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, for assistance in the preparation of this report.

Synonyms of Eosinophilic Esophagitis

  • allergic esophagitis

Disorder Subdivisions

  • atopic and non-atopic
  • proton pump inhibitor (PPI) responsive and non-responsive

General Discussion

Eosinophilic esophagitis (EoE) is a chronic disorder of the digestive system in which large numbers of a particular type of white blood cell called eosinophils are present in the esophagus. The esophagus is the tube that carries food from the mouth to the stomach. Eosinophils are an important part of the immune system and play a role in immune regulation and fighting certain infection. This condition is characterized by vomiting, stomach or chest pain, failure to thrive (particularly in children), difficulty swallowing, and food getting stuck in the throat.

Organizations related to Eosinophilic Esophagitis

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