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Erythema Multiforme

Abstract

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Synonyms of Erythema Multiforme

Dermatostomatitis, Erythema Multiforme Type
Erythema Multiforme Bullosum
Erythema Polymorphe, Erythema Multiforme Type
Febrile Mucocutaneous Syndrome
Herpes Iris, Erythema Multiforme Type

Disorder Subdivisions

No subdivisions found.

General Discussion

Erythema multiforme (EM) is the name applied to a group of hypersensitivity disorders, affecting mostly children and young adults, and characterized by symmetric red, patchy lesions, primarily on the arms and legs. The cause is unknown, but EM frequently occurs in association with herpes simplex virus, suggesting an immunologic process initiated by the virus. In half of the cases, the triggering agents appear to be medications, including anticonvulsants, sulfonamides, nonsteroidal anti-inflammatory drugs, and other antibiotics. In addition, some cases appear to be associated with infectious organisms such as Mycoplasma pneumoniae and many viral agents.

Erythema multiforme is the mildest of three skin disorders that are often discussed in relation to each other. It is generally the mildest of the three. More severe is Stevens-Johnson syndrome. The most severe of the three is toxic epidermal necrolysis (TEN).

Organizations related to Erythema Multiforme

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