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NORD is very grateful to Morie Gertz, MD, Chair of Medicine, Mayo Clinic, for assistance in the preparation of this report.
Synonyms of Waldenström's Macroglobulinemia
- Waldenstrom's syndrome
- No subdivisions found.
Waldenström's macroglobulinemia (WMG) is a malignant disorder of the blood, a type of lymphoma and characterized by the presence of abnormally large numbers of a particular kind of white blood cell known as B lymphocytes. As these cells accumulate in the body, excessive quantities of an antibody known as IgM are produced. Large amounts of IgM causes the blood to become thick (hyperviscosity) and affects the flow of blood through the smaller blood vessels, leading to the symptoms of the disorder. The organs fed by these small blood vessels do not receive sufficient blood and oxygen, potentially resulting in partial or complete failure of the organ.
Waldenström's Macroglobulinemia Resources
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