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Mucous Membrane Pemphigoid

Abstract

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NORD is very grateful to Carl M. Allen, DDS, MSD, Professor and Chair, Division of Oral and Maxillofacial Pathology and Radiology, The Ohio State University College of Dentistry, for assistance in the preparation of this report.

Synonyms of Mucous Membrane Pemphigoid

cicatricial pemphigoid
CP
MMP
mucous membrane pemphigoid

Disorder Subdivisions

Brunsting-Perry syndrome
localized cicatricial pemphigoid
vegetating cicatricial pemphigoid

General Discussion

Mucous membrane pemphigoid (MMP) is a group of rare chronic autoimmune disorders characterized by blistering lesions that primarily affect the various mucous membranes of the body. The mucous membranes of the mouth and eyes are most often affected. The mucous membranes of the nose, throat, genitalia, and anus may also be affected. The symptoms of MMP vary among affected individuals depending upon the specific site(s) involved and the progression of the disease. Blistering lesions eventually heal, sometimes with scarring. Progressive scarring may potentially lead to serious complications affecting the eyes and throat. In some cases, blistering lesions also form on the skin, especially in the head and neck area. The exact cause of MMP is unknown.

MMP has been known by many different names within the medical literature including benign mucous membrane pemphigoid, cicatricial (scarring) pemphigoid, and ocular cicatricial pemphigoid. In March of 2002, a consensus group of researchers determined that mucous membrane pemphigoid was the best designation for this group of disorders. The term "benign" mucous membrane pemphigoid was deemed inappropriate because of the potential for serious complications in some cases. The term "cicatricial" pemphigoid excluded affected individuals who do not develop scarring. Site-specific terms such as "ocular" cicatricial pemphigoid excluded individuals with multiple site involvement.

Organizations related to Mucous Membrane Pemphigoid

American Autoimmune Related Diseases Association, Inc.
- 22100 Gratiot Ave.
- Eastpointe, MI 48021
- Phone #: 586-776-3900
- 800 #: 800-598-4668
- e-mail: aarda@aarda.org
- Home page: http://www.aarda.org/
Australasian Blistering Diseases Foundation
- St. George Hospital,
- Department of Dermatology
- Gray Street
- Kogarah
- Sydney, NSW 2217 Australia
- Phone #: 029-113-2088
- 800 #: N/A
- e-mail: info@blisters.org.au
- Home page: http://www.blisters.org.au/BDHome.html
Autoimmune Information Network, Inc.
- PO Box 4121
- Brick, NJ 08723
- Phone #: N/A
- 800 #: N/A
- e-mail: autoimmunehelp@aol.com
- Home page: N/A
AutoImmunity Community
- Phone #: N/A
- 800 #: N/A
- e-mail: moderator@autoimmunitycommunity.org
- Home page: http://www.autoimmunitycommunity.org
European Society for Immunodeficiencies
- 1-3 rue de Chantepoulet
- Geneva, CH 1211 Switzerland
- Phone #: 410-229-080484
- 800 #: N/A
- e-mail: esid@kenes.com
- Home page: http://www.esid.org
Genetic and Rare Diseases (GARD) Information Center
- PO Box 8126
- Gaithersburg, MD 20898-8126
- Phone #: 301-251-4925
- 800 #: 888-205-2311
- e-mail: N/A
- Home page: http://rarediseases.info.nih.gov/GARD/
International Pemphigus & Pemphigoid Foundation
- 2701 Cottage Way
- Suite 16
- Sacramento, CA 95825 USA
- Phone #: 916-922-1298
- 800 #: --
- e-mail: pemphigus@pemphigus.org
- Home page: http://www.pemphigus.org
NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases
- Information Clearinghouse
- One AMS Circle
- Bethesda, MD 20892-3675 USA
- Phone #: 301-495-4484
- 800 #: 877-226-4267
- e-mail: NIAMSinfo@mail.nih.gov
- Home page: http://www.niams.nih.gov/

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