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Yellow Nail syndrome

Abstract

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NORD is very grateful to Fabien Maldonado, MD, Assistant Professor of Medicine, Consultant, Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, Minnesota, for assistance in the preparation of this report.

Synonyms of Yellow Nail syndrome

  • lymphedema with yellow nails
  • YNS

Disorder Subdivisions

  • No subdivisions found.

General Discussion

Yellow nail syndrome is an extremely rare disorder characterized by malformations affecting the fingernails and toenails, abnormalities affecting the lungs and the airways (respiratory tract), and swelling or puffiness in different parts of the body because of the accumulation of protein-rich fluid (lymph) in the soft layers of tissue under the skin (lymphedema). Yellow nail syndrome usually affects older adults. The exact cause of yellow nail syndrome is not known. Occasionally, yellow nail syndrome has been reported to run in families suggesting that genetic factors may play a role in the development of the disorder in these cases.

Organizations related to Yellow Nail syndrome

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