Hajdu Cheney Syndrome
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Synonyms of Hajdu Cheney Syndrome
- acroosteolysis dominant type
- acroosteolysis with osteoporosis and changes in skull and mandible
- Cheney syndrome
- No subdivisions found.
Hajdu-Cheney syndrome (HCS) is a rare, heritable disorder of connective tissue; only about 50 cases have been reported in the medical literature. The breakdown of bone (osteolysis), especially the outermost bones of the fingers and toes (acroosteolysis), is a major characteristic of HCS.
In addition, patients with HCS frequently have skull deformities, short stature, joint laxity, reduction of bone mass (osteoporosis) and other signs. Most affected individuals have normal mental development but a small proportion show mild mental retardation.
Although the majority of cases are of unknown cause, the presence of multiple cases in one family suggests that autosomal dominant genetic transmission may be possible.
Organizations related to Hajdu Cheney Syndrome
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