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Lynch Syndrome

Abstract

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NORD is very grateful to Albert de la Chapelle, MD, PhD, Distinguished University Professor, Department of Molecular Virology, Immunology, and Medical Genetics, and Heather Hampel, MS, CGC, Clinical Associate Professor, Genetic Counselor, Department of Internal Medicine, at the Ohio State University Comprehensive Cancer Center, for assistance in the preparation of this report.

Synonyms of Lynch Syndrome

  • hereditary non-polyposis colon cancer
  • HNPCC
  • Muir-Torre syndrome
  • Turcot syndrome

Disorder Subdivisions

  • No subdivisions found.

General Discussion

Lynch syndrome is an autosomal dominant cancer predisposition syndrome characterized by an increased risk for colon cancer and cancer of the stomach, small intestine, upper urinary tract, liver, brain and skin. Women with this condition also have an increased risk for cancer of the lining of uterus (endometrium) and ovaries.

Organizations related to Lynch Syndrome

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