Simpson Dysmorphia Syndrome
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Synonyms of Simpson Dysmorphia Syndrome
- Bulldog Syndrome
- DGSX Golabi-Rosen Syndrome, Included
- Dysplasia Gigantism Syndrome, X-Linked
- SGB Syndrome
- Simpson-Golabi-Behmel Syndrome
- Simpson Dysmorphia Syndrome Type 1 (SDYS1)
- Simpson Dysmorphia Syndrome Type 2
Simpson dysmorphia syndrome types 1 and 2 are two forms of a rare, X-linked recessive, inherited disorder characterized by unusually large fetuses (prenatal overgrowth) and unusually large babies (postnatal overgrowth). In addition, affected individuals have characteristic facial features, more than two nipples (super-numerary nipples), and multisystemic malformations that may vary from child to child. Chief among these are cardiac malformations, mild to moderate mental retardation, cleft palate, and more than the five fingers and/or toes (polydactyly).
Symptoms associated with the more common form, Simpson dysmorphia syndrome type 1 (SDYS1), are less severe than those presented in SDYS2.
Individuals usually reach an above-average height. The general distinguishing features typically become less apparent in adulthood.
Organizations related to Simpson Dysmorphia Syndrome
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