Major symptoms may include excessive oral tendencies with an urge to put all kinds of objects into the mouth, hypermetamorophosis (a need to explore everything), memory loss, emotional changes, extreme sexual behavior, indifference, placidity, visual distractibility and visual agnosia (difficulty identifying and processing visual information). An almost uncontrollable appetite for food may also be noted. There may also be other symptoms associated with dementia (loss of reason) as well.
Klüver-Bucy syndrome is the result of damage to the temporal lobes of the brain. This may be the result of trauma to the brain itself, or the result of other degenerative brain diseases, tumors, or it can be caused by some brain infections, most commonly herpes simplex encephalitis (a viral brain infection).
Klüver-Bucy syndrome is a very rare disease that affects males and females equally.
Treatment of Klüver-Bucy syndrome is supportive and psychotropics that may be effective for some of the associated symptoms.
Information on current clinical trials is posted on the Internet at www.clinicaltrials.gov. All studies receiving U.S. Government funding, and some supported by private industry, are posted on this government web site.
For information about clinical trials being conducted at the NIH Clinical Center in Bethesda, MD, contact the NIH Patient Recruitment Office:
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Slaughter J, et al., Selective serotonin reuptake inhibitor treatment of post-traumatic Klüver-Bucy syndrome. Brain Inj. 1999;13:59-62.
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NINDS Klüver-Bucy Syndrome Information Page. http://www.ninds.nih.gov/disorders/kluver_bucy/kluver_bucy.htm Last updated July 2, 2008. Accessed May 21, 2015.