NORD gratefully acknowledges Roy D. Altman, MD, Professor of Medicine, Division of Rheumatology and Immunology, University of California, Los Angeles, for assistance in the preparation of this report.
Synonyms of Paget’s Disease
- Paget's disease of bone
Subdivisions of Paget’s Disease
Paget's disease of bone is a chronic, slowly progressive skeletal condition of abnormally rapid bone destruction (osteolytic) and reformation (osteoblastic). The new bone may occur in one or more regions of the body and is structurally abnormal, dense and fragile. This abnormal development may cause bone pain, arthritis, deformities and fractures. The bones most frequently affected are in the spine, skull, pelvis and lower legs. The exact cause of Paget's disease is not known.
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