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Balo Disease

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Copyright 1986, 1994, 2003, 2007



Synonyms of Balo Disease
  • Concentric Sclerosis
  • Encephalitis Periaxialis Concentrica
  • Leukoencephalitis Periaxialis Concentric

Disorder Subdivisions



General Discussion
Balo Disease is a rare and progressive variant of multiple sclerosis. It usually first appears in adulthood, but childhood cases have also been reported. While multiple sclerosis typically is a disease that waxes and wanes, Balo Disease is different in that it tends to be rapidly progressive. Symptoms may include headache, seizures, gradual paralysis, involuntary muscle spasms, and cognitive loss. The alternative names for Balo Disease, concentric sclerosis or Balo concentric sclerosis, refer to the fact that Balo Disease is characterized by bands of intact myelin (the sheath of fatty substances surrounding nerve fibers) alternating with rings of loss of myelin (demyelination) in various parts of the brain and brain stem. The symptoms of Balo Disease vary, according to the areas of the brain that are affected. Symptoms may progress rapidly over several weeks or more slowly over two to three years.
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Organizations related to Balo Disease
  • American Autoimmune Related Diseases Association, Inc.
    22100 Gratiot Avenue
    Eastpointe MI 48021
    Phone #: 586-776-3900
    800 #: 800-598-4668
    e-mail: aarda@aarda.org
    Home page: http://www.aarda.org/
  • AutoImmunity Community
    None
    None None None
    Phone #: (91-9) -552-9057
    800 #: N/A
    e-mail: bandrews@autoimmunitycommunity.org
    Home page: http://autoimmunitycommunity.org
  • Genetic and Rare Diseases (GARD) Information Center
    PO Box 8126
    Gaithersburg MD 20898-8126
    Phone #: 301-251-4925
    800 #: 888-205-2311
    e-mail: ordr@od.nih.gov
    Home page: http://rarediseases.info.nih.gov/Default.aspx
  • National Institute of Neurological Disorders and Stroke (NINDS)
    P.O. Box 5801
    Bethesda MD 20824
    Phone #: 301-496-5751
    800 #: 800-352-9424
    e-mail: me20t@nih.gov
    Home page: http://www.ninds.nih.gov/
  • United Leukodystrophy Foundation
    2304 Highland Drive
    Sycamore IL 60178
    Phone #: 815-895-3211
    800 #: 800-728-5483
    e-mail: office@ulf.org
    Home page: http://www.ulf.org/

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Last modified Wednesday, November 26, 2008