The second annual South Carolina Rare Disease Symposium will have speakers from the National Organization of Rare Disorders (NORD), Greenwood Genetics, Clemson University, advocacy groups, and more. We will discuss our state report card, rare disease in legislation, personal experiences with clinical trials and caretaking for those with a rare disease. There will be an open discussion with presenters where attendees will have the opportunity to ask questions. The symposium is free and open to the public. Please register with the following link: https://redcap.musc.edu/surveys/?s=C398XH94NKCEKRRE.