Aplasia cutis congenita

Disease Overview

Aplasia cutis congenita is a condition in which there is congenital (present from birth) absence of skin, with or without the absence of underlying structures such as bone.[466] It most commonly affects the scalp, but any location of the body can be affected.[467] While most people with aplasia cutis congenita have no other abnormalities, some people have congenital malformations involving the cardiovascular (heart), gastrointestinal, genitourinary, and central nervous systems.[466] The cause of this condition is unclear and appears to be multifactorial (many different factors appear to play a role); contributing factors may include teratogens, genes, trauma, and compromised blood flow to the skin.[466] 

Synonyms

• Aplasia cutis congenita nonsyndromic
• Congenital defect of skull and scalp
• Scalp defect congenital