Autoimmune hemolytic anemia

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Disease Overview

Autoimmune hemolytic anemia (AIHA) occurs when your immune system makes antibodies that attack your red blood cells. This causes a drop in the number of red blood cells, leading to hemolytic anemia.[5702][5703][5704][5705] Symptoms may include unusual weakness and fatigue with tachycardia and breathing difficulties, jaundice, dark urine and/or splenomegaly. AIHA can be primary (idiopathic) or result from an underlying disease or medication.[5703] The condition may develop gradually or occur suddenly. There are two main types of autoimmune hemolytic anemia: warm antibody hemolytic anemia and cold antibody hemolytic anemia.[5703][5704][5705] Treatment may include corticosteroids such as prednisone, splenectomy, immunosuppressive drugs and/or blood transfusions.[5704]


Synonyms

  • Anemia hemolytic autoimmune
  • Acquired autoimmune hemolytic anemia
  • Idiopathic autoimmune hemolytic anemia
  • Familial auto-immune hemolytic anemia (subtype)
  • Immuno-hemolytic anemia

For more information, visit GARD.

National Organization for Rare Disorders