Chronic graft versus host disease

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Disease Overview

Chronic graft versus host disease (GVHD) is a complication that can occur after a stem cell or bone marrow transplant in which the newly transplanted donor cells attack the transplant recipient’s body.[5853] Symptoms may include skin rash, mouth sores, dry eyes, liver inflammation, development of scar tissue in the skin and joints, and damage to the lungs.[5853][5854] The exact cause of chronic GVHD is unknown.[5854] It likely results from a complex immune-mediated interaction between the donor and recipient cells.[5854][5855] Chronic GVHD is treated with prednisone or other similar anti-inflammatory or immunosuppressive medications.[5853][5854]  


Synonyms

  • Chronic GVHD

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National Organization for Rare Disorders