Disseminated peritoneal leiomyomatosis

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Disease Overview

Disseminated peritoneal leiomyomatosis (DPL) is a rare condition which
is characterized by nodules or small lumps of smooth muscle cells located on
the peritoneum (lining of the abdominal wall) and abdominal organs.The
condition is usually benign (noncancerous) but in rare cases has become
cancerous. Although it can be seen in post-menopausal women and very
rarely in men, DPL occurs most often in women of childbearing age. Most
women with DPL are pregnant, taking the birth control pill, or have uterine leioyomas or estrogen-secreting tumors. Some people with DPL have no
signs or symptoms of the condition. When
present, symptoms may include abdominal and pelvic pain; rectal or vaginal
bleeding; and less commonly constipation. The cause of DPL is unknown but may
be linked to hormonal and genetic factors.
Some cases of DPL resolve when hormone levels are returned to normal. However, surgery may be suggested based on the size and location of the
tumor.[10273][10274][10275]


Synonyms

  • Diffuse peritoneal leiomyomatosis
  • Leiomyomatosis peritonealis disseminate
  • DPL
  • LPD

For more information, visit GARD.

National Organization for Rare Disorders