Hemangioma thrombocytopenia syndrome

Disease Overview

Hemangioma thrombocytopenia syndrome is characterized by profound thrombocytopenia in association with two rare vascular tumors: kaposiform hemangioendotheliomas and tufted angiomas. The profound thrombocytopenia can cause life threatening bleeding and progress to a disseminated coagulopathy in patients with these tumors.[2616][2617] The condition typically occurs in early infancy or childhood, although prenatal cases (diagnosed with the aid of ultrasonography), newborn presentations, and rare adult cases have been reported.[2618]

Synonyms

• Kasabach Merritt syndrome
• Thrombocytopenia-hemangioma syndrome
• Kasabach Merritt phenomenon
• KMP