This information is provided by the National Institutes of Health (NIH) Genetic and Rare Diseases Information Center (GARD).
Good syndrome is a rare, adult-onset primary immunodeficiency suspected in patients who exhibit hypogammaglobulinemia and low levels of B cells along with a benign thymic tumor (thymoma) on chest X-ray.[4726][4727][4728] Symptoms include frequent opportunistic infections involving the sinuses and lungs, including severe CMV disease, P. carinii pneumonia, and mucocutaneous candidiasis.[4727][4728] While the cause of Good syndrome remains unknown, there is some evidence that a defect of the bone marrow is involved.[4728] Treatment includes removal of the thymic tumor and immunoglobulin replacement.[4726][4727][4728]
For more information, visit GARD.
