This information is provided by the National Institutes of Health (NIH) Genetic and Rare Diseases Information Center (GARD).
Iridocorneal endothelial (ICE) syndrome describes a group of eye diseases that are characterized by three main features:
ICE syndrome, is more common in women than men, most commonly diagnosed in middle age, and is usually present in only one eye. The condition is actually a grouping of three closely linked conditions: Cogan-Reese syndrome; Chandler’s syndrome; and essential (progressive) iris atrophy. The cause of ICE syndrome is unknown, however there is a theory that it is triggered by a virus that leads to swelling of the cornea. While there is no way to stop the progression of the condition, treatment of the symptoms may include medication for glaucoma and corneal transplant for corneal swelling.
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