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Morgagni-Stewart-Morel (MSM) syndrome is a disorder characterized by thickening of the frontal bone of the skull (hyperostosis frontalis interna), as well as obesity and excessive hair growth (hypertrichosis).[3186] Other signs and symptoms may include seizures, headaches, diabetes insipidus, and sex gland disturbances.[3191] The cause of Morgagni-Stewart-Morel syndrome is not fully understood. Some instances of dominant inheritance have been reported, but whether it is autosomal dominant or X-linked dominant is not known.[3188] Treatment may include medication for headaches and seizures and surgery to remove the excessive bone of the skull.[3191][3189]
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