Opsoclonus-myoclonus syndrome

Disease Overview

Opsoclonus-myoclonus syndrome (OMS) is a rare disorder that affects the nervous system. Symptoms include rapid, multi-directional eye movements (opsoclonus), quick, involuntary muscle jerks (myoclonus), uncoordinated movement (ataxia), irritability, and sleep disturbance. The onset of OMS is usually abrupt and often severe. The disease may become chronic.[1744] OMS typically occurs in association with tumors (neuroblastomas), or following a viral or bacterial infection.[1745][1746][7345] Treatment may include corticosteroids or ACTH (adrenocorticotropic hormone). When there is a tumor present, treatment may include chemotherapy, surgery, and/or radiation. In some cases, when the underlying cause of OMS is treated, symptoms improve.[1744][1745][1746]

Synonyms

• Opsoclonus myoclonus syndrome
• OMS
• Kinsbourne syndrome
• OMA syndrome
• Opsoclonus-myoclonus-ataxia syndrome
• POMA syndrome
• Paraneoplastic opsoclonus-myoclonus
• Paraneoplastic opsoclonus-myoclonus-ataxia syndrome
• Ataxo-opso-myoclonus syndrome
• Dancing eye-dancing feet syndrome
• Dancing eye syndrome