Rare Disease Database

Rare Disease Database

SAPHO syndrome

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Disease Overview

SAPHO syndrome involves any combination of: Synovitis (inflammation of the joints), Acne, Pustulosis (thick yellow blisters containing pus) often on the palms and soles, Hyperostosis (increase in bone substance) and Osteitis (inflammation of the bones). The cause of SAPHO syndrome is unknown and treatment is focused on managing symptoms.[7160]

Synonyms

  • Acquired hyperostosis syndrome
  • Synovitis, Acne, Pustlosis, Hyperostosis, and Osteomyelitis
  • Synovitis acne pustulosis hyperostosis osteitis

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