This information is provided by the National Institutes of Health (NIH) Genetic and Rare Diseases Information Center (GARD).
Sclerosing mucoepidermoid carcinoma with eosinophilia (SMECE)
is a type of cancer that most commonly affects the thyroid gland, but
has been reported in the salivary gland as well. Signs and
symptoms include a painless neck mass. Many people with mucoepidermoid carcinomas
are women with Hashimoto’s thyroiditis. The prevalence of SMECE is
unknown, but only around 50 cases have been described in the medical
literature. SMECE most commonly presents between 40 to 75 years of
age. SMECE was initially considered a “low-grade” tumor, however cases
of SMECE spreading locally to lymph nodes and to distant
organs have been described. While data is limited, with treatment it appears that prognosis is typically good.
For more information, visit GARD.