Sclerosing mucoepidermoid carcinoma with eosinophilia

Disease Overview

Sclerosing mucoepidermoid carcinoma with eosinophilia (SMECE)
is a type of cancer that most commonly affects the thyroid gland, but
has been reported in the salivary gland as well.[8937][8941] Signs and
symptoms include a painless neck mass.[8941] Many people with mucoepidermoid carcinomas
are women with Hashimoto’s thyroiditis.[8937][8940] The prevalence of SMECE is
unknown, but only around 50 cases have been described in the medical
literature.[8938] SMECE most commonly presents between 40 to 75 years of
age.[8941] SMECE was initially considered a “low-grade” tumor, however cases
of SMECE spreading locally to lymph nodes and to distant
organs have been described.[8937][8940] While data is limited, with treatment it appears that prognosis is typically good.[8937][8938][8939][8941]

Synonyms

• SMECE