This information is provided by the National Institutes of Health (NIH) Genetic and Rare Diseases Information Center (GARD).
Sydenham’s chorea is a neurological disorder characterized by rapid, jerky, irregular, and involuntary movements (chorea), especially of the face and limbs. Additional symptoms may include muscle weakness, slurred speech, headaches, and seizures. Children with Sydenham’s chorea often have emotional or behavioral problems such as obsessive-compulsive disorder, distractibility, irritability, and inappropriate outbursts of laughing or crying. Sydenham’s chorea mostly affects children and adolescents and usually follows a Streptococcal infection by anywhere form 1-8 months. Sydenham’s chorea is one of the major clinical signs of acute rheumatic fever. The uncontrolled movements are often worse during periods of stress, fatigue, or excitement. In some cases, only one side of the body is affected. Sydenham’s chorea usually resolves within 3 weeks to 3 months. However, symptoms may last longer in some cases.
For more information, visit GARD.