Transposition of the great arteries

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Disease Overview

Transposition of the great arteries (TGA) is a type of congenital heart defect in which there is a reversal of the normal connections of the aorta and the pulmonary artery with the heart. The aorta and pulmonary artery are reversed, which causes oxygen-poor blood to be circulated to the body and oxygen-rich blood to be circulated between the lungs and the heart, rather than to the body. Symptoms are apparent at birth and include great difficulty breathing and severe cyanosis (a bluish discoloration of the skin).[3675] The exact cause of TGA in most cases is unknown.[3676] Surgery is done to correct the abnormality during the first few days of life.[3675]


Synonyms

  • DTGA
  • Dextro-looped transposition of the great arteries

For more information, visit GARD.

National Organization for Rare Disorders