Loey Dietz Syndrome Foundation

About Loey Dietz Syndrome Foundation

Loey Dietz Syndrome Foundation (LDSF) is a voluntary organization whose mission is to encourage the education of medical professionals and lay communities about Loey Dietz syndrome (LDS) in order to aid in the identification, diagnosis, and treatment of this disorder. LDSF also fosters research on LDS and provides a support network for those impacted by it. Loeys-Dietz syndrome is a genetic disorder of connective tissue caused by a mutation in either of the two genes that tell the body how to make proteins called transforming growth factor beta receptor 1 (TGFBR1) and transforming growth factor beta receptor 2 (TGFBR2.) Because connective tissue is found throughout the body, LDS features can occur in the musculoskeletal, skin and cardiovascular systems.