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Giant Cell Myocarditis

Abstract

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NORD is very grateful to Leslie T. Cooper Jr., MD, Director, Gonda Vascular Center; Professor of Medicine, Mayo Clinic, for assistance in the preparation of this report.

Synonyms of Giant Cell Myocarditis

  • GCM
  • idiopathic giant cell myocarditis

Disorder Subdivisions

  • No subdivisions found.

General Discussion

Giant cell myocarditis is a rare cardiovascular disorder that occurs for unknown reasons (idiopathic). It is characterized by inflammation of the heart muscle (myocardium), a condition referred to as myocarditis. Inflammation is caused by widespread infiltration of giant cells associated with other inflammatory cells and heart muscle cell destruction. Giant cells are abnormal masses produced by the fusion of inflammatory cells called macrophages. Individuals with giant cell myocarditis may develop abnormal heartbeats, chest pain and, eventually, heart failure. Many individuals eventually require a heart transplant. The disorder most often occurs in young adults.

Organizations related to Giant Cell Myocarditis

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