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Neuromyelitis Optica

Abstract

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NORD is very grateful to Brian Weinshenker, MD, FRCP(C), Professor of Neurology, Mayo Clinic, for assistance in the preparation of this report.

Synonyms of Neuromyelitis Optica

  • (Asian, Japanese) opticospinal MS
  • Devic disease
  • Devic syndrome
  • optic neuromyelitis
  • opticomyelitis

Disorder Subdivisions

  • monophasic neuromyelitis optica
  • neuromyelitis optica spectrum disorders
  • relapsing neuromyelitis optica

General Discussion

Neuromyelitis optica, also known as Devic disease (DD), is a chronic disorder of nerve tissue characterized by inflammation of the optic nerve (optic neuritis) and inflammation of the spinal cord (myelitis). There appear to be two forms of this disease. In the classical, but less common monophasic type, one or both optic nerves and the spinal cord are affected by a series of attacks over a short period of time (days or weeks) but, after the initial outburst, there is no recurrence. The second form is more common and is characterized by repeated attacks separated by periods of remission. In this form, the interval between attacks may be weeks, months or years. In its early stages, Devic disease may be confused with multiple sclerosis.

Organizations related to Neuromyelitis Optica

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