International Society for Systemic Auto-Inflammatory Diseases

The International Society for Systemic Auto-Inflammatory Diseases (ISSAID) is a voluntary, non-profit organization that gathers resources designed specifically for autoinflammatory diseases to facilitate contacts between physicians, biologists and basic researchers dealing with these disorders. It provides support to share and rapidly disseminate information, thoughts, feelings and experiences to improve the quality of life of patients affected by autoinflammatory diseases and promote advances in the search for the causes and cure. Information on past and forthcoming meetings and a number of new applications (e.g. a centralized list of existing mutation and patient registries, image libraries, quality control schemes for molecular diagnosis�) are made available through its portal website. Their INFEVERS website is an online registry for all known sequence variants in genes associated with auto-inflammatory diseases. It provides detailed mutation description, genomic, cDNA and protein sequences, a graph for each gene, and useful links and reference sequences. Autoinflammatory diseases are defined as illnesses caused by primary dysfunction of the innate immune system.