International 22q11.2 Deletion Syndrome Foundation, Inc.

The International 22q11.2 Deletion Syndrome Foundation, Inc. is a non-profit organization whose mission is to improve the quality of life for individuals affected by the 22q11.2 deletion syndrome through family and professional partnerships. Chromosome 22q11.2 deletion syndrome is a disorder caused by a small piece of chromosome 22 missing. Chromosome 22q11.2 deletion syndrome is associated with a range of problems including: congenital heart disease, palate abnormalities, immune system dysfunction including autoimmune disease, low calcium (hypocalcemia) and other endocrine abnormalities such as thyroid problems and growth hormone deficieny, gastrointestinal problems, feeding difficulties, kidney abnormalities, hearing loss, seizures, skeletal abnormalities, minor facial differences, and learning and behavioral differences. The symptoms of this condition are extremely variable, even among members of the same family.