Bisous For Léo

Bisous For Léo is an Ancillary Arm of the INADcure Foundation, the only U.S. based non-profit dedicated exclusively to the Infantile
Neuroaxonal Dystrophy (INAD) community. Bisous For Léo was formed in 2018 as an ancillary arm to support their mission. Together
we are funding scientific research for treatments and a cure for INAD and other forms of PLA2G6-related neurodegeneration (PLAN).
As explained by Dr. Paul T. Kotzbauer, MD, PhD, and professor in the department of neurology at Washington University School of
Medicine, “I have been able to identify a definitive link between Parkinson’s disease and INAD. Accumulation of the alpha-synuclein protein, a defining feature of Parkinson’s disease, also occurs in INAD, affecting the same regions of the central nervous system. Thus, further understanding of these two neurodegenerative disorders will help to develop new treatments and ultimately a cure.”  As affirmed by J. Paul Taylor, M.D., Ph.D., Faculty Member, Chair of Cell and Molecular Biology Department at St. Jude Children’s Research Hospital and Howard Hughes Medical Institute Investigator, “Mutations in PLA2G6 have been associated with other brain disorders, such as Parkinson’s and Alzheimer’s diseases. Research shows that some INAD patients present Lewy bodies and neurofibrillary tangles in the brain, which suggests a shared pathogenesis. Supporting science aimed towards a better understanding of INAD and PLA2G6 gene mutations could also benefit the other brain diseases in which PLA2G6 has been implicated. Our mission is to kiss INAD goodbye.
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