Loeys-Dietz Syndrome Foundation

Loeys-Dietz Syndrome Foundation (LDSF) is a voluntary organization whose mission is to encourage the education of medical professionals and lay communities about Loeys-Dietz syndrome (LDS) in order to aid in the identification, diagnosis, and treatment of this disorder. LDSF also fosters research on LDS and provides a support network for those impacted by it. Loeys-Dietz syndrome is a genetic disorder of connective tissue caused by a mutation in either of the two genes that tell the body how to make proteins called transforming growth factor beta receptor 1 (TGFBR1) and transforming growth factor beta receptor 2 (TGFBR2.) Because connective tissue is found throughout the body, LDS features can occur in the musculoskeletal, skin and cardiovascular systems.