pancreatic acinar cell carcinoma

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Disease Overview

An adenocarcinoma arising from the pancreas. It is characterized by the presence of relatively uniform malignant cells which form acinar patterns. It usually occurs during adulthood. Signs and symptoms include abdominal pain, weight loss, nausea, and diarrhea. It may metastasize to regional lymph nodes and the liver. A minority of patients develop lipase hypersecretion syndrome. This syndrome may be seen in patients with liver metastases and it is characterized by excessive secretion of lipase in the serum, polyarthralgia, and subcutaneous fat necrosis.


Synonyms

  • PAAC
  • Pancreatic acinar cell cancer
  • acinar cell adenocarcinoma of pancreas
  • acinar cell adenocarcinoma of the pancreas
  • acinar cell carcinoma of pancreas
  • acinar cell carcinoma of the pancreas
  • carcinoma of pancreatic acinar cell
  • pancreas acinar cell adenocarcinoma
  • pancreatic acinar cell adenocarcinoma
  • pancreatic acinar cell carcinoma

GARD Disease Summary

The Genetic and Rare Diseases Information Center (GARD) has information and resources for patients, caregivers, and families that may be helpful before and after diagnosis of this condition. GARD is a program of the National Center for Advancing Translational Sciences (NCATS), part of the National Institutes of Health (NIH).

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Orphanet

Orphanet has a summary about this condition that may include information on the diagnosis, care, and treatment as well as other resources. Some of the information and resources are available in languages other than English. The summary may include medical terms, so we encourage you to share and discuss this information with your doctor. Orphanet is the French National Institute for Health and Medical Research and the Health Programme of the European Union.

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