childhood epilepsy with centrotemporal spikes

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Disease Overview

A childhood-onset epilepsy syndrome that is characterized by onset of seizures between 3 and 14 years (peak 8-9 years) that usually resolve by age 13 years, but can occasionally occur up to age 18 years of age. Both sexes are affected. Antecedent, birth and neonatal history is normal. A history of febrile seizure (in 5-15%) may be seen. A history of Panayiotopoulos syndrome may be present in a very small number of cases. Neurological exam and head size is normal. Development and cognition prior to onset of seizures is normal. During the course of the active epilepsy, behavioral and neuropsychological deficits may be found, particularly in language and executive functioning. These deficits improve when seizures remit.


Synonyms

  • BCECTS
  • BECRS
  • BECTS
  • BRE
  • Rolandic epilepsy
  • benign Rolandic epilepsy
  • benign Rolandic epilepsy (BRE)
  • benign Rolandic epilepsy of childhood (BREC)
  • benign childhood epilepsy with centrotemporal spike
  • benign childhood epilepsy with centrotemporal spikes
  • benign epilepsy of childhood with centrotemporal spikes
  • benign epilepsy of childhood with centrotemporal spikes (BECCT)
  • benign epilepsy with centro-temporal spikes (BECTS)
  • benign epilepsy with centrotemporal spikes
  • benign familial epilepsy of childhood with rolandic spikes
  • centralopathic epilepsy
  • centrotemporal epilepsy
  • centrotemporal epilepsy, isolated cases
  • childhood epilepsy with centrotemporal spikes
  • sylvan seizures
  • temporal-central focal epilepsy

GARD Disease Summary

The Genetic and Rare Diseases Information Center (GARD) has information and resources for patients, caregivers, and families that may be helpful before and after diagnosis of this condition. GARD is a program of the National Center for Advancing Translational Sciences (NCATS), part of the National Institutes of Health (NIH).

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Orphanet

Orphanet has a summary about this condition that may include information on the diagnosis, care, and treatment as well as other resources. Some of the information and resources are available in languages other than English. The summary may include medical terms, so we encourage you to share and discuss this information with your doctor. Orphanet is the French National Institute for Health and Medical Research and the Health Programme of the European Union.

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OMIM

Online Mendelian Inheritance In Man (OMIM) has a summary of published research about this condition and includes references from the medical literature. The summary contains medical and scientific terms, so we encourage you to share and discuss this information with your doctor. OMIM is authored and edited at the McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine.

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