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primary mediastinal large B-cell lymphoma

The information provided on this page is for informational purposes only. The National Organization for Rare Disorders (NORD) does not endorse the information presented. The content has been gathered in partnership with the MONDO Disease Ontology. Please consult with a healthcare professional for medical advice and treatment.

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Disease Overview

A large B-cell non-Hodgkin lymphoma arising in the mediastinum. Morphologically it is characterized by a massive diffuse lymphocytic proliferation associated with compartmentalizing fibrosis. Response to intensive chemotherapy, with or without radiotherapy, is usually good. (WHO, 2001)

Synonyms

  • B-cell diffuse large cell lymphoma of mediastinum
  • B-cell diffuse large cell lymphoma of the mediastinum
  • Med-DLBCL
  • PMBL
  • PMLCL
  • large cell lymphoma of the mediastinum
  • mediastinal (thymic) large B-cell lymphoma
  • mediastinal B-cell diffuse large cell lymphoma
  • mediastinal diffuse large cell lymphoma with sclerosis
  • mediastinal diffuse large-cell lymphoma with sclerosis
  • mediastinal large B-cell lymphoma
  • primary mediastinal (thymic) large B-cell lymphoma
  • primary mediastinal B-cell lymphoma
  • primary mediastinal clear cell lymphoma of B-cell type
  • primary mediastinal large B-cell lymphoma
GARD Disease Summary

The Genetic and Rare Diseases Information Center (GARD) has information and resources for patients, caregivers, and families that may be helpful before and after diagnosis of this condition. GARD is a program of the National Center for Advancing Translational Sciences (NCATS), part of the National Institutes of Health (NIH).

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Orphanet

Orphanet has a summary about this condition that may include information on the diagnosis, care, and treatment as well as other resources. Some of the information and resources are available in languages other than English. The summary may include medical terms, so we encourage you to share and discuss this information with your doctor. Orphanet is the French National Institute for Health and Medical Research and the Health Programme of the European Union.

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