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central nervous system germinoma

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Disease Overview

A malignant germ cell tumor arising from the central nervous system. It is composed of uniform cells resembling primitive germ cells. These cells have large, vesicular nuclei, prominent nucleoli and a clear, glycogen-rich cytoplasm. Additional features are lymphoid or lymphoplasmacytic infiltrates and, less frequently, scattered syncytiotrophoblastic giant cells. (Adapted from WHO)

Synonyms

  • central nervous system germinoma
  • central nervous system germinoma (disease)
  • germinoma of CNS
  • germinoma of central nervous system
  • germinoma of the CNS
  • germinoma of the central nervous system
  • intracranial germinoma
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