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yolk sac tumor of central nervous system

The information provided on this page is for informational purposes only. The National Organization for Rare Disorders (NORD) does not endorse the information presented. The content has been gathered in partnership with the MONDO Disease Ontology. Please consult with a healthcare professional for medical advice and treatment.

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Disease Overview

A malignant germ cell tumor of the central nervous system composed of primitive-appearing epithelial cells – putatively representing yolk sac endoderm – set in a loose, variably cellular, and often conspicuously myxoid matrix, resembling extra-embryonic mesoblast. Eosinophilic hyaline globules immunoreactive for AFP are a diagnostic feature. (WHO)

Synonyms

  • CNS yolk Sac tumor
  • CNS yolk Sac tumour
  • central nervous system yolk Sac tumor
  • central nervous system yolk Sac tumour
  • endodermal sinus tumor of CNS
  • endodermal sinus tumor of central nervous system
  • endodermal sinus tumour of CNS
  • endodermal sinus tumour of central nervous system
  • intracranial endodermal sinus tumor
  • intracranial endodermal sinus tumour
  • intracranial yolk sac tumor
  • intracranial yolk sac tumour
  • yolk Sac tumor of CNS
  • yolk Sac tumor of central nervous system
  • yolk Sac tumor of the CNS
  • yolk Sac tumor of the central nervous system
  • yolk Sac tumour of CNS
  • yolk Sac tumour of central nervous system
  • yolk Sac tumour of the CNS
  • yolk Sac tumour of the central nervous system
  • yolk sac tumor of CNS
  • yolk sac tumour of CNS
GARD Disease Summary

The Genetic and Rare Diseases Information Center (GARD) has information and resources for patients, caregivers, and families that may be helpful before and after diagnosis of this condition. GARD is a program of the National Center for Advancing Translational Sciences (NCATS), part of the National Institutes of Health (NIH).

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Orphanet

Orphanet has a summary about this condition that may include information on the diagnosis, care, and treatment as well as other resources. Some of the information and resources are available in languages other than English. The summary may include medical terms, so we encourage you to share and discuss this information with your doctor. Orphanet is the French National Institute for Health and Medical Research and the Health Programme of the European Union.

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