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Aquagenic pruritus causes intense itching without any visible skin changes after contact with water of any temperature. The symptoms may begin immediately after contact and can last for an hour or more.[9706] The cause of aquagenic pruritus is unknown; however, familial cases have been described.[9706][9708] Aquagenic pruritis is sometimes a symptom of other conditions such as polycythemia vera. Diagnosis is based on the symptoms and a clinical examination. Overall, treatment is a challenge. Skin creams, antihistamines, phototherapy, changing the pH of the water, and various medications have been tried with varying degrees of success.[9706]
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