Behr syndrome

Disease Overview

Behr syndrome is a disorder characterized by early-onset optic atrophy along with neurological features, including ataxia, spasticity, and intellectual disability.[2412][11767] Other signs and symptoms may be present and vary from person to person. This condition is caused by mutations in the OPA1 gene. It is inherited in an autosomal recessive manner.[2412] Treatment depends on the specific signs and symptoms seen in the patient.[11767]

Synonyms

• OBSOLETE: Behr syndrome
• Optic atrophy, infantile hereditary, Behr complicated form of
• Optic atrophy in early childhood, associated with ataxia, spasticity, mental retardation, and posterior column sensory loss