This information is provided by the National Institutes of Health (NIH) Genetic and Rare Diseases Information Center (GARD).
Glutaric acidemia type III is a rare metabolic condition characterized by persistent, isolated accumulation or excretion of glutaric acid.[9121][9122] No specific phenotype has been described, as symptoms vary and some individuals remain symptom-free.[9121][9122][9123][9124] Unlike other types of glutaric acidemia, this type is caused by a peroxisomal rather than a mitochondrial dysfunction.[9123][9124] Mutations in the C7ORF10 gene on chromosome 7p14 have been identified in some people with glutaric acidemia type III and the condition follows an autosomal recessive pattern of inheritance.[9122][9123][9124] Treatment with riboflavin has been helpful in some patients.[9123]
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