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Huntington disease (HD) is an inherited condition that causes progressive degeneration of neurons in the brain. Signs and symptoms usually develop between ages 35 to 44 years and may include uncontrolled movements, loss of intellectual abilities, and various emotional and psychiatric problems. People with HD usually live for about 15 to 20 years after the condition begins. It is caused by changes (mutations) in the HTT gene and is inherited in an autosomal dominant manner. Treatment is based on the symptoms present in each person and may include various medications.[8726][8727]
There is also a less common, early-onset form of HD which begins in childhood or adolescence. For more information on this form, please visit GARD’s juvenile Huntington disease Web page.
For more information, visit GARD.