Jones syndrome

Disease Overview

Jones syndrome is a very rare condition characterized by gingival fibromatosis (enlargement and overgrowth of the gums) and progressive, sensorineural hearing loss.[7733] The onset of gingival fibromatosis usually occurs with the eruption of the permanent teeth. Excessive growth of the gums may cause displacement of teeth, over-retention of primary teeth, and increased spacing.[7743] Jones syndrome is inherited in an autosomal dominant manner, but the underlying genetic cause is not yet known.[7733] Only a few families with Jones syndrome have been reported.

Synonyms

• Gingival fibromatosis with progressive deafness
• GFD
• Gingival fibromatosis with sensorineural hearing loss
• Familial gingival fibromatosis associated with progressive deafness