bone giant cell tumor

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Disease Overview

A benign but locally aggressive tumor that arises from the bone and is composed of mononuclear cells admixed with macrophages and osteoclast-like giant cells. It usually arises from the ends of long bones or the vertebrae. Clinical presentation includes pain, edema, and decreased range of motion in the affected joint.

Synonyms

GCT of bone
Osteoclastoma, benign
benign bone giant cell tumor
benign bone giant cell tumour
giant cell myeloma
giant cell neoplasm of bone
giant cell tumor of bone
giant cell tumor of bone (morphologic abnormality)
giant cell tumor of bone NOS (morphologic abnormality)
giant cell tumor of the bone
giant cell tumor, benign
giant cell tumour of bone
giant cell tumour of bone (morphologic abnormality)
giant cell tumour of bone NOS (morphologic abnormality)
giant cell tumour of the bone
osteoclastoma

GARD Disease Summary

The Genetic and Rare Diseases Information Center (GARD) has information and resources for patients, caregivers, and families that may be helpful before and after diagnosis of this condition. GARD is a program of the National Center for Advancing Translational Sciences (NCATS), part of the National Institutes of Health (NIH).

View report

Orphanet

Orphanet has a summary about this condition that may include information on the diagnosis, care, and treatment as well as other resources. Some of the information and resources are available in languages other than English. The summary may include medical terms, so we encourage you to share and discuss this information with your doctor. Orphanet is the French National Institute for Health and Medical Research and the Health Programme of the European Union.