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Ewing sarcoma/peripheral primitive neuroectodermal tumor of bone

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Disease Overview

A spectrum of malignant tumors arising from the bone and characterized morphologically by the presence of small round cells. Ewing sarcoma and peripheral primitive neuroectodermal tumor represent the ends of a spectrum, with Ewing sarcoma lacking evidence of neural differentiation and the markers that characterize the peripheral primitive neuroectodermal tumor. Ewing sarcoma and peripheral primitive neuroectodermal tumor may share cytogenetic abnormalities, proto-oncogene expression, cell culture and immunohistochemical abnormalities. Pain and the presence of a mass are the most common clinical symptoms.


Synonyms

  • Ewing sarcoma/peripheral primitive neuroectodermal tumor of bone
  • Ewing's sarcoma/peripheral primitive neuroectodermal tumor of bone
  • Ewing's sarcoma/peripheral primitive neuroectodermal tumour of bone
  • bone tissue Ewing sarcoma/peripheral primitive neuroectodermal tumor
  • bone tissue Ewing sarcoma/peripheral primitive neuroectodermal tumour

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