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vitamin K-dependent clotting factors, combined deficiency of, type 1

The information provided on this page is for informational purposes only. The National Organization for Rare Disorders (NORD) does not endorse the information presented. The content has been gathered in partnership with the MONDO Disease Ontology. Please consult with a healthcare professional for medical advice and treatment.

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Disease Overview

Combined vitamin K-dependent clotting factors deficiency (VKCFD) is a congenital bleeding disorder resulting from variably decreased levels of coagulation factors II, VII, IX and X, as well as natural anticoagulants protein C, protein S and protein Z.

Synonyms

  • FMFD 3
  • GGCX congenital vitamin K-dependent coagulation factors combined deficiency
  • VKCFD1
  • Vkcfd
  • congenital vitamin K-dependent coagulation factors combined deficiency caused by mutation in GGCX
  • factors II, VII, IX, and X, combined deficiency of
  • familial multiple coagulation Factor deficiency 3
  • glutamic acid, deficient gamma-carboxylation of
  • hereditary combined deficiency of factors II, VII, IX and X
  • hereditary combined deficiency of vitamin K-dependent clotting factors
  • multiple coagulation Factor deficiency 3
  • vitamin K-dependent clotting factors, combined deficiency of, 1
  • vitamin K-dependent clotting factors, combined deficiency of, type 1
  • vitamin K-dependent coagulation defect
GARD Disease Summary

The Genetic and Rare Diseases Information Center (GARD) has information and resources for patients, caregivers, and families that may be helpful before and after diagnosis of this condition. GARD is a program of the National Center for Advancing Translational Sciences (NCATS), part of the National Institutes of Health (NIH).

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OMIM

Online Mendelian Inheritance In Man (OMIM) has a summary of published research about this condition and includes references from the medical literature. The summary contains medical and scientific terms, so we encourage you to share and discuss this information with your doctor. OMIM is authored and edited at the McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine.

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