NORD gratefully acknowledges Rodger J. Elble, MD, PhD, Professor of Neurology, Director, Parkinson Disease and Movement Disorders Center, Southern Illinois University School of Medicine, for assistance in the preparation of this report.
Synonyms of Binswanger Disease
- Binswanger encephalopathy
- multi-infarct dementia, Binswanger type
- subcortical arteriosclerotic encephalopathy, SAE
- subcortical dementia
- subcortical ischemic vascular disease
- vascular dementia, Binswanger type
Binswanger disease is a progressive neurological disorder caused by arteriosclerosis and thromboembolism affecting the blood vessels that supply the white-matter and deep structures of the brain (basal ganglia and thalamus). Most patients experience progressive loss of memory and intellectual abilities (dementia), urinary urgency or incontinence, and an abnormally slow, shuffling, unsteady pattern of walking, usually over a 5-10 year period. Due to their vascular etiology, the symptoms and physical findings associated with Binswanger disease may suddenly worsen due to stroke, stabilize and then improve for a brief time, but the patient's overall condition continues to progress as the blood vessels become increasingly obstructed.
1989, 1996, 1997, 2003, 2007, 2009, 2011, 2012, 2016
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